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CDC collects, compiles, and analyzes data on influenza activity year round in the United States.Timing of influenza activity and predominant circulating influenza viruses vary by season. Influenza activity in the United States began to increase in mid-December, remained elevated through February 4, 2016, and is expected to continue for several more weeks.Neither patient was hospitalized; both recovered fully, and there was no evidence of human-to-human transmission in either instance.WHO collaborating laboratories in the United States are requested to submit a subset of influenza-positive respiratory specimens to CDC for further virus characterization.All 66 (100%) influenza B/Yamagata-lineage viruses were antigenically similar to B/Phuket/3073/2013, the recommended influenza B component of the 2016–17 Northern Hemisphere quadrivalent vaccine.The WHO Collaborating Center for Surveillance, Epidemiology, and Control of Influenza at CDC tested 807 influenza virus specimens (94 influenza A (H1N1)pdm09, 519 influenza A (H3N2), and 194 influenza B viruses) collected in the United States from October 1, 2016, through February 4, 2017, for resistance to the influenza neuraminidase inhibitor antiviral medications oseltamivir, zanamivir, and peramivir, drugs currently approved for use against seasonal influenza.During October 2, 2016–February 4, 2017, influenza A (H3N2) viruses were identified most frequently, but influenza A (H1N1)pdm09 and influenza B viruses were also reported.No antiviral resistance to oseltamivir, zanamivir, or peramivir has been identified among influenza viruses tested to date.
All 74 (100%) influenza A (H1N1)pdm09 viruses were antigenically similar to A/California/7/2009, the recommended influenza A (H1N1) component of the 2016–17 Northern Hemisphere vaccine.
Age was reported for 13,306 influenza-positive patients, among whom 1,048 (7.9%) were aged 0–4 years, 4,041 (30.4%) were aged 5–24 years, 4,029 (30.3%) were aged 25–64 years, and 4,188 (31.5%) were aged ≥65 years.
Influenza A (H3N2) viruses predominated in each age group, representing a range of 82.3% of influenza-positives in persons aged 0–4 years to 93.6% in persons aged ≥65 years.
What are the implications for public health practice?
Elevated influenza activity in parts of the United States is expected for several more weeks.
Influenza vaccination remains the most effective way to prevent influenza illness.